A study to compare the effects of 2 drugs -Iv Fentanyl and Iv Remifentanil in Patients Undergoing nose surgeries

Comparison of post procedure sedation and respiratory depression during Functional Endoscopic Sinus Surgery (FESS),Rhinoplasty and Septoplasty when using Remifentanil and Fentanyl A randomized controlled double blind study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084928

Enrollment

Registered

2025-04-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: NIL: NIL Control Intervention1: Iv Fentanyl: Iv Fentanyl 1mcg/kg will be administered to patients undergoing FESS,rhinoplasty and septoplasty .After closure ,surgeon will rate the surgi

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I - II Patients undergoing FESS , rhinoplasty and septoplasty

Exclusion criteria

Exclusion criteria: patient refusal patient expected to require postoperative ventilation allergy to study drugs clinically significant cardiac arrhythmias pregnancy, breastfeeding significant renal/hepatic dysfunction psychiatric instability

Design outcomes

Primary

Measure	Time frame
To compare the effects of IV Remifentanil and IV Fentanyl on postoperative sedation and respiratory depression in Functional Endoscopic Sinus Surgery (FESS) surgery ,Rhinoplasty and SeptoplastyTimepoint: Post extubation of endotracheal tube the Modified Aldrete Score at 1,5,15 minutes will be recorded to measure postoperative respiratory depression and sedation Time taken from the administration of reversal agent till time of extubation will be recorded .	—

Measure

Time frame

To compare the effects of IV Remifentanil and IV Fentanyl on postoperative sedation and respiratory depression in Functional Endoscopic Sinus Surgery (FESS) surgery ,Rhinoplasty and SeptoplastyTimepoint: Post extubation of endotracheal tube the Modified Aldrete Score at 1,5,15 minutes will be recorded to measure postoperative respiratory depression and sedation Time taken from the administration of reversal agent till time of extubation will be recorded .

—

Secondary

Measure	Time frame
To compare surgical field satisfaction score & pain score when using IV Remifentanil & IV Fentanyl in Functional Endoscopic Sinus surgery ,Rhinoplasty & SetoplastyTimepoint: Pain score using visual analogue scale at 15,30 minutes will be recorded Post closure surgical field satisfaction by surgeon using likert score on scale of 1-5	—

Countries

India

Contacts

Public ContactJovita Maria Monteiro

P D Hinduja Hospital and Medical Research Centre Mahim

dranjalipingle@gmail.com9833733915

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026