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Comparison of Ropivacaine with Dexmedetomidine versus Ropivacaine with Magnesium Sulfate for Pain Relief After Lumbar Spine Surgery

A Randomized study to Compare Analgesic Efficacy of Ropivacaine with Dexmedetomidine Versus Ropivacaine with Magnesium fulfate in Surgical Site Infiltration in Patients Undergoing Lumbar Spine Fixation Surgery under General Anaesthesia - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/084862
Enrollment
120
Registered
2025-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G952- Other and unspecified cord compression

Interventions

Intervention1: Ropivacaine combined with Dexmedetomidine: Patients in the intervention group will receive a combination of ropivacaine (a local anesthetic) and dexmedetomidine (an alpha-2 adrenergic a

Sponsors

SMS Medical College And Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing to give written and informed consent Patients undergoing lumbar spine fixation surgery Patients with ASA physical status 1 or 2

Exclusion criteria

Exclusion criteria: Non cooperative patients BMI more than 35kg/m2 History of allergy to any other drugs used during the study

Design outcomes

Primary

MeasureTime frame
To asses and compare mean NRS score at different intervals between the study groups To assess and compare in mean time of first rescue analgesia intravenous Diclofenac between the study groups To asses and compare the difference in mean total number of doses of intravenous Diclofenac in 24 hours postoperatively between the study groupsTimepoint: Just after extubation ,2hours ,6hours ,12hours, 24hours

Secondary

MeasureTime frame
To assess and compare post operative hemodynamic vitals between the study groups To determine the proportion of patients experiencing side effects between study groupsTimepoint: Up to 24 hours of extubation

Countries

India

Contacts

Public ContactDr Manish Kumar

SMS medical college and hospital

Purohit.shobha@gmail.com9414059823

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026