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Comparative evaluation of propolis, calcium hydroxide and its combination on post operative pain

Comparative evaluation of propolis and its combination with calcium hydroxide as an intracanal medicament on postoperative pain in permanent mandibular molars with symptomatic irreversible pulpitis and apical periodontitis - a single blinded randomized controlled trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/084842
Enrollment
45
Registered
2025-04-15
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 1.Propolis as an intracanal medicament 2.combination of propolis and calcium hydroxide As an intracanal medicament: Propolis is natural material derived from honey bee hives which has a

Sponsors

Dr Vishal Raut
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients older than 18 years and younger than 60 years of either gender. Mandibular molar teeth diagnosed with symptomatic irreversible pulpitis with apical periodontitis. Patient not taken any medication like analgesic, antibiotic since past 3 days. Cooperative healthy patients who are willing to participate in the study and sign the consent form.

Exclusion criteria

Exclusion criteria: Patients younger than 18 or older than 60 years. Subjects taking any medication such as antibiotics, analgesics, narcotics, sedatives, or antidepressants. History of significant medical problem (ASA III or greater). Tooth that not indicated for further restoration. Subjects unable to give informed consent.

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the effect of propolis and its combination with calcium hydroxide as an intracanal medicament on postoperative pain in permanent mandibular molars with symptomatic irreversible pulpitis and apical periodontitis.Timepoint: To evaluate and compare the effect of propolis and its combination with calcium hydroxide as an intracanal medicament on postoperative pain in permanent mandibular molars with symptomatic irreversible pulpitis and apical periodontitis at 12,24 and 48 hrs

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDrDeepak sharma

Bharati vidyapeeth dental college and hospital, Navi mumbai

deepakdent@gmail.com9820091359

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026