Health Condition 1: G00-G99- Diseases of the nervous system
Conditions
Interventions
Intervention1: GROUP A : SUBCUTANEOUS NITROGLYCERIN: 1 ml of 2% lidocaine local subcutaneous anesthesia at the wrist will be administered followed by subcutaneous injection of 0.5 ml of 500 micrograms
Sponsors
Department of Radiodiagnosis PGIMER Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: Indicated for diagnostic cerebral angiography
Exclusion criteria
Exclusion criteria: 1) Radial artery diameter less than 1.8mm 2) Systolic Blood Pressure less than 90 mm Hg 3) Heart rate less than 50 BPM 4) Left Ventricular Ejection Fraction less than 35 percentage 5) Raynauds Phenomenon in the Upper limb 6) Vasculitis 7) Severe atherosclerotic segmental stenotic disease in the upper limb arteries 8) Only functional limb or injured limb 9) Contraindications of diagnostic DSA
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the incidence and severity of radial artery spasm (RAS) Assessed by: 1. Angiographic evidence showing narrowing of radial artery. 2. Pain perceived by the patient. Pain will be graded from 0-10 on a visual analogue scale. Pain more than or equal to 8 will indicate severe spasm. 3. Limitation in advancing or withdrawing the catheters or guidewires as detected by the operator. It will be graded as mild difficulty, moderate difficulty and completlely stuck catheter. Timepoint: Day 1 and 1 month | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Change in Radial artery diameter after subcutaneous injection measured by doppler ultrasound 2)Radial artery puncture attempts 3)Procedure duration in minutes 4)Hemodynamic changes measured by blood pressure and pulse monitoring during the procedure Timepoint: at 24 hours and one month after the procedure | — |
Countries
India
Contacts
Public ContactDr VIKAS BHATIA
PGIMER CHANDIGARH
Outcome results
None listed