Effectiveness of 0.5% Levobupivacaine vs 0.75% Ropivacaine in lower abdomen short surgeries for early discharge - clinical trial

Comparison of home readiness following intrathecal 0.5% Levobupivacaine and 0.75% Ropivacaine in infraumbilical short surgeries - Double blind randomized control trial - nil

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084783

Enrollment

Registered

2025-04-15

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I00-I99- Diseases of the circulatory system

Interventions

Intervention1: INTRATHECAL ROPIVACAINE 0.75% HEAVY: In patients belonging to group Ropivacaine, 22.5mg(3mL) of 0.75% hyperbaric Ropivacaine will be administrated intrathecally in L3-L4 space. Monitori

Eligibility

Inclusion criteria

Inclusion criteria: patients of ASA 1 and 2 physical status, infra umbilical surgeries lasting less than 2 hours

Exclusion criteria

Exclusion criteria: patients with allergic history to local anaesthetics, local site skin infection, bleeding and coagulation disorders, pregnancy, spine deformities

Design outcomes

Primary

Measure	Time frame
To measure and compare the time taken for complete motor regression produced with intrathecal 15mg 0.5% hyperbaric Levobupivacaine vs intrathecal 22.5mg 0.75% hyperbaric RopivacaineTimepoint: At baseline, 5mins,10mins,15mins,30mins,1hour,1:30hours,2hours,2:30hours,3hours and postoperatively 30min,1hour,1:30hours,2hours	—

Secondary

Measure	Time frame
1)Time taken for onset of spinal anaesthesia 2)Maximum sensory blockade level 3)Time taken to achieve maximum sensory blockade level 4)Change in hemodynamic parameters among both the groups 5)Time taken for unassissted ambulation 6)Time taken for voiding urineTimepoint: ONSET OF MOTOR BLOCK -5,10,15,30,45 mins ONSET OF SENSORY BLOCK - 2,4,6,8,10,15,20,25,30,35 mins HEMODYNAMICS - baseline,2,5,10,15,20,25,30mins,1hr,1.5hrs,2hrs	—

Measure

Time frame

1)Time taken for onset of spinal anaesthesia 2)Maximum sensory blockade level 3)Time taken to achieve maximum sensory blockade level 4)Change in hemodynamic parameters among both the groups 5)Time taken for unassissted ambulation 6)Time taken for voiding urineTimepoint: ONSET OF MOTOR BLOCK -5,10,15,30,45 mins ONSET OF SENSORY BLOCK - 2,4,6,8,10,15,20,25,30,35 mins HEMODYNAMICS - baseline,2,5,10,15,20,25,30mins,1hr,1.5hrs,2hrs

—

Countries

India

Contacts

Public ContactDR NIKITHA STEPHEN

Mahatma Gandhi medical college and research institute, Pillayarkuppam, Pondicherry

yasha.vdk@gmail.com9825767631

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026