Study to Evaluate the Effect of a Herbal Pack in Knee Osteoarthritis of Postmenopausal Women

Single Arm Clinical Trial To Assess The Effect Of Vachadi Upanaha In Post-menopausal Knee Osteoarthritis In Relation To WOMAC Scale And CTX-II Biomarker - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084776

Enrollment

Registered

2025-04-15

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.Females aged 50 to 70 years 2.Radiologic changes in the knee on X-ray, classified as Kellgren-Lawrence grade I, II and III 3.Able and willing to participate and provide signed informed consent.

Exclusion criteria

Exclusion criteria: 1.Radiologic changes in the knee on X-ray, classified as Kellgren-Lawrence grade IV 2.Diagnosed cases of tuberculosis, rheumatoid arthritis 3.Patients under NSAID-s for the past six months 4.H/O any knee surgery, acute inflammation, trauma or fractures to the knee joints in the last six months. 5.Use of calcium supplements 6.Patients underwent Collagen therapy

Design outcomes

Primary

Measure	Time frame
Reduction in pain, stiffness, and improvement in physical function as measured by the WOMAC ScaleTimepoint: 1st assessment on day 1 2nd assessment on day 8 3rd assessment on day 15	—

Secondary

Measure	Time frame
Reduction in cartilage degradation as measured by Urinary CTX-II biomarker levelsTimepoint: 1st assessment on day 1 2nd assessment on day 8 3rd assessment on day 15	—

Countries

India

Contacts

Public ContactDr Vishnu U

Amrita School of Ayurveda

nambu24@gmail.com9496096694

Outcome results