Regenerative potential of Metformin gel, Zoledronic acid gel and Mineral trioxide aggregate.

Histological evaluation of pulpal response to direct pulp capping using Metformin gel, Zoledronic acid gel and Mineral trioxide aggregate - A randomised controlled trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084771

Enrollment

Registered

2025-04-15

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: METFROMIN GEL: Metformin gel, formulated from pure powder Metformin, is applied to pulpal exposure for pulp capping. Histological evaluation is conducted after therapeutic tooth extrac

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing for voluntary participation and have signed informed consent Age group:18-24 years old Either sex Systemically healthy individuals Periodontally healthy individuals Absence of any pathology around the area of interest

Exclusion criteria

Exclusion criteria: The teeth with the following criteria are to be excluded from the study: Decayed or fractured teeth Previous restorative history Symptomatic teeth Teeth with any other pathology Teeth not conducive for rubber dam isolation Negative response to pulp vitality testing Presence of systemic diseases

Design outcomes

Primary

Measure	Time frame
ASYMPTOMATIC VITAL TOOTH WITH NORMAL PULPAL RESPONSE ON VITALITY TESTTimepoint: 1 week, 1 month and 3 months	—

Secondary

Measure	Time frame
REPARATIVE DENTIN BRIDGE FORMATION EVALUATED HISTOLOGICALLYTimepoint: 1 week, 1 month and 3 months	—

Countries

India

Contacts

Public ContactDR PRIYANKA SHARMA

TAMILNADU GOVERNMENT DENTAL COLLEGE AND HOSPITAL, CHENNAI

kavithaendo@yahoo.com9841161131

Outcome results