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Helping Nerves Heal Better: Using a Special Gel (polyethylene glycol) to Improve Recovery After Arm Nerve Injuries

Feasibility of Polyethylene glycol(PEG) fusion on autografts in brachial plexus injury patients for accelerated recovery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/084675
Enrollment
20
Registered
2025-04-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G00-G99- Diseases of the nervous system

Interventions

Intervention1: surgical invention: Polyethylene glycol fusion (PEG) is a synthetic polymer gaining attention for its potential to aid in nerve repair. It is a flexible, water-soluble compound commonly

Sponsors

Dr Deepak Agrawal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients with Acute onset post traumatic nerve lesion 2 Patients requiring nerve graft harvest for neurotization 3 Pan BPI and partial BPI 4 Patients with cleanly severed peripheral nerves requiring surgical repair. 5 Age: 18 65 years old, without significant comorbidities. 6.No prior nerve damage at the site of injury.

Exclusion criteria

Exclusion criteria: 1 Patient above 60 years and below 18. 2 Patient allergic to Polyethylene glycol.

Design outcomes

Primary

MeasureTime frame
Successful PEG-fusion is expected to restore nerve conduction and improve sensory and motor function faster than traditional repair techniques. Patients receiving PEG-fusion should show measurable improvements in nerve recovery during follow-up assessments.Timepoint: 6 weeks

Secondary

MeasureTime frame
Time taken by this method for recovery is less as compare to other methodsTimepoint: 4-6 weeks

Countries

India

Contacts

Public ContactDr Deepak Agrawal

All India Institute of Medical Sciences New Delhi

drdeepak@gmail.com9811282043

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026