Effect of Ayurvedic treatment on memory and thinking problems in old age: A clinical trial

Efficacy and safety of an ayurvedic regimen (Brahmarasayana + Mandukaparni Churna) in mild cognitive impairment (MCI) among elderly: An open-label randomized control trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084667

Enrollment

214

Registered

2025-04-13

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F068- Other specified mental disorders due to known physiological condition

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Screened positive for mild cognitive impairment, Having normal communication and language skills to be able to understand and correctly answer the researchers questions during the screening process, and Provide signed informed consent for the study

Exclusion criteria

Exclusion criteria: Cognitive impairment due to epilepsy, brain trauma or vascular dementia Severe organ lesions and mental illness severe hearing and vision impairment diabetes, poorly controlled hypertension

Design outcomes

Primary

Measure	Time frame
Montreal Cognitive Assessment (MoCA) score Mini Mental State Examination (MMSE) score Activities of Daily Living (ADL) score Instrumental Activities of Daily Living (IADL) score High-sensitivity C-reactive protein (hsCRP) level Interleukin-6 (IL-6) level Brain-derived neurotrophic factor (BDNF) level MRI scanTimepoint: Baseline (MoCA,MMSE,ADL, IADL,hsCRP,IL-6,BDNF,MRI scan-brain) 90 days (MoCA, MMSE,ADL, IADL,hsCRP,IL-6,BDNF) 180 days (MoCA,MMSE,ADL, IADL,hsCRP,IL-6,BDNF,MRI scan-brain)	—

Measure

Time frame

Montreal Cognitive Assessment (MoCA) score Mini Mental State Examination (MMSE) score Activities of Daily Living (ADL) score Instrumental Activities of Daily Living (IADL) score High-sensitivity C-reactive protein (hsCRP) level Interleukin-6 (IL-6) level Brain-derived neurotrophic factor (BDNF) level MRI scanTimepoint: Baseline (MoCA,MMSE,ADL, IADL,hsCRP,IL-6,BDNF,MRI scan-brain) 90 days (MoCA, MMSE,ADL, IADL,hsCRP,IL-6,BDNF) 180 days (MoCA,MMSE,ADL, IADL,hsCRP,IL-6,BDNF,MRI scan-brain)

—

Secondary

Measure	Time frame
CBC LFT KFT Ayurvedic prakriti WHOQOL-BREF Ayurvedic Agni Kosta NidraTimepoint: Baseline and every month till 180 days(CBC,LFT,KFT) Baseline only (Ayurvedic prakriti) Baseline, 90 days and 180 days (WHOQOL-BREF, Ayurvedic agni, kosta, nidra)	—

Countries

India

Contacts

Public ContactDr Pankaj Bhardwaj

AIIMS Jodhpur

pankajbhardwajdr@gmail.com8003996903

Outcome results