Health Condition 1: L83- Acanthosis nigricans
Conditions
Interventions
Intervention1: Fractional carbon dioxide oxide laser: Fractional carbon dioxide oxide laser will be done on the site every 2 weeks for upto 4 times and the efficacy will be assessed by ANASI scoring s
Sponsors
Mahatma Gandhi Medical College and Research Institute
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged between 18 and 60 years presenting with acanthosis nigricans of the neck and face
Exclusion criteria
Exclusion criteria: 1.patients with any skin infection in the neck and face at the time of the session. 2.patients with previous herpes simplex infection on the study site. 3.patients with endocrine disorders, 4. patients with malignant AN. 5. patients who previously applied the following topical medications- retinoids, hydroquinone, or corticosteroid and depigmenting agents in the last 1 month. 6. patients who took the following medications- contraceptive pill, nicotinic acid, corticosteroids, estrogen, niacin, protease inhibitors, within 1 month prior to study or systemic retinoids within 6 months prior to study. 7. patients who are allergic to tretinoin and topical anesthetic creams, 8. patients with keloidal tendency 9.pregnancy and lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of Fractional Carbon di oxide laser and retinoic acid peel in acanthosis nigricansTimepoint: Fractional Carbon di oxide laser- 4 times at an interval of 2 weeks Retinoic acid peel- 4 times at an interval of 3 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To document the adverse effects of fractional carbon di oxide laser and retinoic acid peel in acanthosis nigricansTimepoint: Fractional carbon di oxide laser- 4 times at an interval of 2 weeks Retinoic acid peel- 4 times at an interval of 3 weeks | — |
Countries
India
Contacts
Public ContactGnanasuriyan Ramachandran
Mahatma Gandhi Medical College and Research Institute
Outcome results
None listed