Health Condition 1: B956- Staphylococcus aureus as the causeof diseases classified elsewhere
Conditions
Interventions
Intervention1: AUC/MIC group: The area under the curve / Minimum inhibitory concentration of Vancomycin Dose depends upon the treating physician, sample will be taken after achieving 1 steady state i.
Sponsors
Dr Deepak Kumar
Eligibility
Inclusion criteria
Inclusion criteria: Patients microbiologically confirmed with methicillin-resistant staphylococcus aureus infection.
Exclusion criteria
Exclusion criteria: 1. Patients undergoing any kind of renal replacement therapy or having prior Acute Kidney Injury AKI) 2. Patients concerned with meningitis or any central nervous system (CNS) infection 3. Pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Better Clinical Outcomes (Clinical Improvement and laboratory parameters) in trough concentration versus AUC/MIC concentrations of vancomycin 35% discordance between trough and AUCTimepoint: The outcome will be assessed on days 7, 14, and 21, i.e. after 1 week, 2 weeks, and 3 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Nephrotoxicity in trough versus AUC/MIC concentration of vancomycin Microbiological cure in trough concentration versus AUC/MIC concentration of vancomycin Timepoint: The outcome will be assessed on days 7, 14, & 21, i.e. after 1 week, 2 weeks, & 3 weeks | — |
Countries
India
Contacts
Public ContactDr Deepak Kumar
All India Institute of Medical Sciences, Jodhpur
Outcome results
None listed