Health Condition 1: E789- Disorder of lipoprotein metabolism, unspecified
Conditions
Interventions
None listed
Sponsors
National Institute of Ayurveda Deemed to Be University (De-Novo) Jaipur
Eligibility
Inclusion criteria
Inclusion criteria: Adults in the age group of 18 to 60 years of either sex. LDL-C more than or equal to 130 mg/dl and less than or equal to 190 mg/dl. Cholesterol more than or equal to 200 mg/dl and less than or equal to 300mg/dl. Triglycerides level more than or equal to 150 mg/dl and less than or equal to 300mg/dl. Those who have voluntarily signed the written informed consent.
Exclusion criteria
Exclusion criteria: Patients having history of Unstable angina, Myocardial infarction and cerebrovascular accidents. Patients having Systolic blood pressure (SBP) & Diastolic blood pressure (DBP) more than or equal to 160 &100 mm of Hg respectively. Patients with uncontrolled diabetes mellitus with FBS level more than 160 mg/dl or HbA1c higher than 8%. Patients having hypothyroidism with TSH level more than or equal to 1.5 times the upper limit of normal. Patients having statins, fibric acid derivatives, cholestyramine, nicotinic acid, proprotein convertase subtilisin/kexin type 9 inhibitors, corticosteroids, diuretics, amiodarone, cyclosporine. Patients with chronic disorders like Nephrotic syndrome, Renal failure, Auto immune disorders, Chronic Liver Disease (AST or ALT levels more than 2 times the upper limit of normal), and other serious diseases. Pregnant women and lactating mother and females of child bearing age willing to conceive during trial period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood level of LDL-C. Timepoint: Baseline and end of eigth week | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood levels of TC, non-HDL-C, HDL-C, TG, fasting blood glucose, high sensitivity C- reactive protein (hs-CRP), apolipoprotein (Apo) A1, Apo B, HDL, TC:HDL-C, SGOT, SGPT, S.Creatinine. Anthropometric parameters including weight,BMI, waist and hip circumference, waist to hip ratio, body fat mass, body fat percentage and QoL based on EQ-5D questionnaire, questionnaire of Medodushti Lakshana. Timepoint: Investigations will be on 0th day and end of 8th week Anthropometric parameters including weight,BMI, waist and hip circumference, waist to hip ratio, body fat mass, body fat percentage and QoL based on EQ-5D questionnaire, questionnaire of Medodushti Lakshana will be assessed on 0th day, 2nd week, 4th week, 6th week and end of 8th week | — |
Countries
India
Contacts
Public ContactDr Sakshi Chahar
National institute of Ayurveda jaipur
Outcome results
None listed