Health Condition 1: M625- Muscle wasting and atrophy, not elsewhere classified
Conditions
Interventions
Intervention1: Resistance training programme: It composed of 4 days training in a week for 8 weeks.the duration is 30 minutes per day.A certified gym trainer will be training the subjects . This has b
Sponsors
Dr Aiswarya.P
Dr V K Sashindaran
Eligibility
Inclusion criteria
Inclusion criteria: All the individuals with type 2 diabetes mellitus with sarcopenia attending, K.S Hegde Medical Academy, Rural health center Ira more than 40 years of age of either sex and willing to participate in the study Diabetes defined as those patients with fasting glucose levels of greater than equal to 126 mg/dl or random blood glucose greater than equal to 200 mg/dl, HbA1c greater than equal to 6.5%. Sarcopenia as defined by EWGSOP SARC F less than 4 or Hand Grip Strength less than27 kg for males ,less than 18 kg for females.
Exclusion criteria
Exclusion criteria: Known cases of physical disabilities, chronic disease (tuberculosis, cancer, chronic renal failure and ischemic heart disease), muscular dystrophies, joint injuries ,patients on insulin therapy,
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biomarkers-coenzyme Q,Irisin, myostatin/follistatin ratio,BDNF,P3NP , miR1/206, miR 21, miR 23a, miR27a,/27b,miR29b-3p, miR 129-5P miR133a3P, miR 214, miR 486a-5pTimepoint: Biomarkers-coenzyme Q,Irisin, myostatin/follistatin ratio,BDNF,P3NP , miR1/206, miR 21, miR 23a, miR27a,/27b,miR29b-3p, miR 129-5P miR133a3P, miR 214, miR 486a-5p | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of the biomarkers before and after interventionTimepoint: Comparison of the biomarkers after 8 weeks of intervention | — |
Countries
India
Contacts
Public ContactDr VK Sashindaran
K.S Hegde Medical Academy Nitte DU
Outcome results
None listed