To study pain relief in children after tonsillectomy by giving Levobupivacaine with Dexmedetomidine or Dexamethasone locally around tonsils.

Comparative study between Levobupivacaine Plus Dexmedetomidine versus Levobupivacaine plus Dexamethasone Infiltration for Post-Tonsillectomy Analgesia - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084633

Enrollment

Registered

2025-04-11

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Levobupivacaine 0.25% 2.5ml plus dexmedetomidine 1mcg/kg only once before surgery for analgesia.: Peritonsillar fossa will be infiltrated with Levobupivacaine 0.25% 2.5ml plus dexmedeto

Eligibility

Inclusion criteria

Inclusion criteria: Physical status ASA 1 and 2.

Exclusion criteria

Exclusion criteria: Refusal for participation Inadequate NBM Bleeding disorder, Active Upper respiratory infection, Emergency surgery.

Design outcomes

Primary

Measure	Time frame
Duration of postoperative analgesia from start of peritonsillar infiltration with study drug till first rescue analgesia given at when CHEOPS score is more than 5 or Wong Baker pain scale more than 4 postoperatively.Timepoint: Time from peritonsillar infiltration of study drugs till first rescue analgesia given postoperatively.Total number of Analgesia in 24hrs postopertively.	—

Secondary

Measure	Time frame
1) Total number of rescue analgesic dosages consumed in 24 hours postoperatively. 2) For the first 24 hours after surgery, the total oral intake (fluids and semisolids). 3) Perioperative side effects: such as hypotension, hypertension, tachycardia, bradycardia, hypoxia, arrhythmia, excessive secretions, bleeding, respiratory depression, nausea, and vomiting will be noted.4) Ramsay sedation scale.5) CHEOPS score and VAS score postoperatively.Timepoint: From the time of study drug administration till 24hrs postoperatively.	—

Measure

Time frame

1) Total number of rescue analgesic dosages consumed in 24 hours postoperatively. 2) For the first 24 hours after surgery, the total oral intake (fluids and semisolids). 3) Perioperative side effects: such as hypotension, hypertension, tachycardia, bradycardia, hypoxia, arrhythmia, excessive secretions, bleeding, respiratory depression, nausea, and vomiting will be noted.4) Ramsay sedation scale.5) CHEOPS score and VAS score postoperatively.Timepoint: From the time of study drug administration till 24hrs postoperatively.

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Countries

India

Contacts

Public ContactDr Sumedha Mehta

Smt kashibai Navale medical College and General Hospital

drsumedhamehta1@gmail.com9923091187

Outcome results