Use of equilibriation point of Desflurane and Sevoflurane as a change over point in low flow anesthesia

Use of Equilibriation point of Sevoflurane and Desflurane as a changeover point to low flow anesthesia- a randomised prospective comparative study on Breast cancer surgeries - NIL

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084594

Enrollment

Registered

2025-04-11

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Low flow anesthesia: Switch over from initial high flow to low flow anesthesia in breast cancer surgeries Control Intervention1: Sevoflurane: initially 1.3 times the minimum alveolar co

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged between 20 and 60 years Willing to informed consent Belonging to ASA 1 and ASA 2 Body Mass Index (BMI) between 18.5 and 25 kg/m2

Exclusion criteria

Exclusion criteria: Patient not willing to give consent Belonging to ASA 3 and 4

Design outcomes

Primary

Measure	Time frame
To compare equilibration point of Sevoflurane and Desflurane as a switch over point to low flow anesthesiaTimepoint: within the time period of the surgery intraoperatively	—

Secondary

Measure	Time frame
Arterial blood gas variation due to low flow anesthesiaTimepoint: 1. immediately after changeover to low flow anesthesia 2. 20 minutes after low flow anesthesia 3. immediate post operative;Hemodynamic parametersTimepoint: every 5 minutes for first 15 minutes, every 10 minutes for next half hour & 15 minutes till end of the surgery;Washout time of inhalational agentTimepoint: after the last suture till the patient responds & follows the verbal commands	—

Measure

Time frame

Arterial blood gas variation due to low flow anesthesiaTimepoint: 1. immediately after changeover to low flow anesthesia 2. 20 minutes after low flow anesthesia 3. immediate post operative;Hemodynamic parametersTimepoint: every 5 minutes for first 15 minutes, every 10 minutes for next half hour & 15 minutes till end of the surgery;Washout time of inhalational agentTimepoint: after the last suture till the patient responds & follows the verbal commands

—

Countries

India

Contacts

Public ContactDr Mamatha H S

Kidwai Memorial Institute of Oncology

drmamathah@yahoo.com9448514758

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026