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To compare & evaluate DFDBA with & without Doxycyline hyclate loaded Proniosomal gel in the chronic periodonitis patients.

Comparative evaluation of Demineralised Freeze Dried Bone Allograft with & without Doxycycline hyclate loaded Proniosomal gel in the treatment of Class II Furcation defects: A Randomized Controlled Trial. - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/084584
Enrollment
28
Registered
2025-04-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Y62-Y69- Misadventures to patients during surgical and medical care

Interventions

Intervention1: Doxycycline gel with DFDBA: Stage III Perioodntitis exhibiting class II furcation defects to be treated with doxycycline gel with DFDBA Intervention Frequency-once time at the site Du

Sponsors

Dr. Vaishnavi Biradar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients with Stage III periodontitis as assessed by Probing Pocket Depth (PPD) 2) 6mm, interdental clinical attachment level (CAL) 3) 5 mm and Horizontal Probing Depth (HPD) 2mm Patients with at least two class II furcation defects in either maxillary or mandibular arch.

Exclusion criteria

Exclusion criteria: 1) Patients with a history of allergies, Systemic diseases or drug usage. 2) Patients who have undergone periodontal surgery in previous 6 months. 3) Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
To evaluate & compare the efficacy of doxycycline hyclate loaded proniosomal gel in combination with DFDBA & DFDBA alone in the treatment of Class II furcation defects radiographically by CBCT.Timepoint: Baseline, 3 months and 6 months

Secondary

MeasureTime frame
To assess Clinical Attachment Level (CAL), Probing Pocket Depth (PPD) ,Horizontal Probing Depth (HPD)and radiographic bone fill in Class II furcation defects when treated with doxycycline hyclate loaded proniosomal gel in combination with DFDBA & DFDBA aloneTimepoint: at baseline 3 months & 6 months

Countries

India

Contacts

Public ContactDr Dhawal Mody

Ranjeet Deshmukh Dental College and Research Centre

periowell@gmail.com8055775977

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026