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Effect of intrathecal chemotherapy in children under anaesthesia on heart rate and blood pressure

Haemodynamic changes after Intrathecal Methotrexate Chemotherapy in Pediatric patients under General Anaesthesia- A Prospective Observational Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/04/084576
Enrollment
50
Registered
2025-04-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C942- Acute megakaryoblastic leukemia

Interventions

None listed

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients aged 1-15 years of age planned for intrathecal methotrexate chemotherapy under general anaesthesia 2. Informed consent from the parents of these children.

Exclusion criteria

Exclusion criteria: 1. Parents not giving informed consent 2. Local site infection at the site of putting the needle

Design outcomes

Primary

MeasureTime frame
1.To evaluate for immediate hemodynamic changes that occur during the intrathecal methotrexate chemotherapy under general anesthesiaTimepoint: 1 hr postoperative—

Secondary

MeasureTime frame
1. To evaluate the major and minor complications of intrathecal methotrexate chemotherapy in pediatric patientsTimepoint: 5 days—

Countries

India

Contacts

Public ContactDr Sofia Jaswal

Homi Bhabha Cancer Hospital and Research Centre, New Chandigarh

sofiapatial@gmai.com9459262870

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026