To compare the pain relieving action of Ibuprofen vs Paracetamol in patients undergoing abdominal hysterectomy after the surgery

To Compare the Efficacy of Intravenous Ibuprofen Vs Intravenous Paracetamol as Post Operative Analgesia in Patients Undergoing Abdominal Hysterectomy - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084571

Enrollment

200

Registered

2025-04-11

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N00-N99- Diseases of the genitourinary system

Interventions

Intervention1: Injection Ibuprofen: Injection Ibuprofen 400 mg administered intravenously post operatively in patients who have undergone abdominal hysterectomy Control Intervention1: Injection Parace

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade 1 or 2 fit patients. 2. Patients undergoing abdominal hysterectomy. 3. Haemodynamically stable patients with all investigations within normal limits. 4. Written informed consents from concerned patients.

Exclusion criteria

Exclusion criteria: 1. Patients not willing to participate in study 2. Patients with ASA grade 3 and above 3. Patients aged less than 30 and more than 60 years. 4. Patients posted for emergency procedures. 5. Patients with known allergy to the study drugs. 6. Patients with difficult intubation. 7. Patients with psychiatric conditions, coagulopathies, naurological, neuromuscular or cardiovascular disease or impairment of hepatic or renal function. 8. Patients with coagulopathies and contraindications to spinal anaesthesia.

Design outcomes

Primary

Measure	Time frame
To compare the analgesic effect of Intravenous Ibuprofen versus Intravenous Paracetamol as post operative analgesia in patients who have undergone abdominal hysterectomy.Timepoint: After administration of intravenous analgesic, comparison between 2 groups of efficacy and duration of action by monitoring VAS scores at 0,2,4,6,8,12,24,48 hours respectively.	—

Secondary

Measure	Time frame
To compare the analgesic effect of Intravenous Ibuprofen versus Intravenous Paracetamol as post operative analgesia in patients who have undergone abdominal hysterectomy.Timepoint: At baseline, 2 hrs, 4 hrs, 6 hrs, 8 hrs, 12 hrs, 24 hrs & 48 hrs after administration of medication	—

Countries

India

Contacts

Public ContactDr Sandip baheti

Dr. DY Patil Medical College, Hospital and Research Centre, Pimpri, Pune

snbacademics12@gmail.com9822014401

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026