Comparison of Peri-implant Mucosal Enhancement Using Concentrated Growth Factor Membrane at Different Stages of Implant Placement: An Interventional Study

Comparative evaluation of peri-implant mucosal enhancement with and without concentrated growth factor membrane at different stages of implant placement an interventional study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084568

Enrollment

Registered

2025-04-11

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: GROUP 2: CGF Placed On The Day Of Implant Placement 1.Stage 1 Surgery: Same surgical protocol as the control group is followed up to implant placement. After implant is placed, CGF me

Eligibility

Inclusion criteria

Inclusion criteria: 1) Systemically healthy patients with no history of uncontrolled medical conditions (e.g., uncontrolled diabetes, cardiovascular disease). 2) Participants aged 18-65 years. 3) Need for one or more dental implants in the mandibular posterior region. 4) Participants with peri-implant mucosal thickness of 1.5mm 2.5mm. 5) Participants with NO ongoing periodontal disease. 6) Presence of stable occlusion(bite). 7) Sufficient bone volume and quality to support the implant based on radiographs. 8) Ability to understand and comply with study procedures, including follow-up visits

Exclusion criteria

Exclusion criteria: 1) Participants with uncontrolled systemic conditions, such as uncontrolled diabetes, cardiovascular diseases, autoimmune disorders, or bleeding disorders. 2) Severe bone loss - Insufficient bone width or height for implant placement or presence of advanced bone atrophy. 3) Use of medications like systemic corticosteroids, immunosuppressants, or bisphosphonates that could impair healing or affect CGF efficacy. 4) History of radiotherapy in the head/neck area or chemotherapy within the last 12 months. 5) Participants who are unable to follow post-operative care instructions or attend follow-up visits. 6) Any ongoing periodontal infection. 7) Pregnant or breastfeeding women. 8) Known allergies to materials used in implant dentistry. 9) Previous implant failures or complications

Design outcomes

Primary

Measure	Time frame
1. Thickness of Peri-Implant MucosaTimepoint: Baseline, 4 Weeks and 3 Months	—

Secondary

Measure	Time frame
1. Width of Keratinized Tissue 2. Healing Progression Timepoint: Baseline, 4 Weeks & 3 Months	—

Countries

India

Contacts

Public ContactDr Parimala Kumar

A.J. Institute of dental sciences

parikodgi76@gmail.com9448915650

Outcome results