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Isobaric levobupivacaine with adjuvant in thoracic spinal for upper abdominal surgeries for early recovery and long duration of post operative pai n relief

Isobaric levobupivacaine versus isobaric levobupivacaine with dexmedetomidine in segmental spinal anaesthesia in patients undergoing upper abdominal surgeries. A Randomised study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/084541
Enrollment
60
Registered
2025-04-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K420- Umbilical hernia with obstruction,without gangrene

Interventions

Intervention1: 0.5% Isobaric Levobupivacaine 1.5ml with 5 mcg dexemedetomidine: will be given in segmental spinal anaesthesia for surgical procedure and outcomes measured for 24 hours Control Interven

Sponsors

AIIMS bibinagar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients undergoing upper abdominal surgeries. Open cholecystectomy Splenectomy Epigastric hernia Lipoma upper abdomen Hydatid cyst of Liver Drainage of amoebic liver abcess Feeding jejunostomy Ileostomy stoma closures Gastrojejunostomy Hepatic resection Gastric outlet obstruction Umbilical hernia Paraumbilical hernia. 2. Age group between 19-65 years. 3. Patients belonging to ASA I-II.

Exclusion criteria

Exclusion criteria: 1. ASA III - IV patients. 2. Pregnant women. 3. Anxious, uncooperative patient. 4. Conversion to general anesthesia. 5. Thoracic spinal deformities. 6. Failed spinal. 7. Coagulopathy

Design outcomes

Primary

MeasureTime frame
a) To assess duration of sensory block with isobaric levobupivacaine and isobaric levobupivacaine with dexmedetomidine. b)To assess total segments blocked for the dose/volume of isobaric levobupivacaine and isobaric levobupivacaine with dexmedetomidine with respect to the level of introduction at thoracic spine Timepoint: After giving spinal anaesthesia segments of sensory block shall be assessed with cold sensation. Both upper level and lower level of dermatomes are assessed and marked. Time taken for 2 segments regression shall be considered for the second time point for duration. (Time point 1:onset of block, time point 2: two segment regression. Difference between the two will be duration of block)—

Secondary

MeasureTime frame
To assess the incidence of hypotension, nausea & vomiting, shivering, early post-operative ambulation & urinary retention.Timepoint: Any fall in NIBP of 20% of baseline will be noted immediately after spinal and measurements are will be taken at an interval of 5 min for the first 30min after spinal anaesthesia & thereafter for every 15min till end of surgery. Patients are followed up for 24 hours to assess secondary outcomes—

Countries

India

Contacts

Public ContactS Kalyani Surya Dhana Lakshmi

AIIMS Bibinagar

sksdhanalakshmi@gmail.com7893720606

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026