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Comparison of different materials used for bone filling to improve gum health

Comparative Evaluation of the Effectiveness of Amnioguard (Guided Tissue Regenration Membrane) in combination with NovaBone Putty and Advanced-Platelet Rich Fibrin (A-PRF Membrane) in combination with NovaBone Putty in the Regeneration of Human Periodontal Infrabony Defects A Randomized Controlled Clinical Trial. - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/084507
Enrollment
24
Registered
2025-04-09
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Novabone putty and Amnioguard: Novabone putty covered with Amnioguard membrane will be placed into the osseous defect in control site with light pressure till it is filled up to the mos

Sponsors

Datta Meghe of Higher Education and Reasearch
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Presence of at least 1 or 2 radiographically detectable interproximal infrabony osseous defect with probing depth 5mm and clinical attachment loss 5mm following initial therapy. 2)Depth of intraosseous component of the defect 3)A radiographic base of the defect at least 3mm coronal to the apex of the tooth. 4)Presence of at least 3mm width of keratinized gingiva around test teeth to allow complete soft tissue coverage of the defect.

Exclusion criteria

Exclusion criteria: 1. Patients who have undergone periodontal therapy in last 6 months. 2. Patients who had received antibiotic therapy during the previous three months. 3. Individuals who are expecting or who have allergies to the drugs in study. 4. Pregnant ladies and lactating mothers . 5. Regular users of mouthwash. 6. Chronic alcoholics.

Design outcomes

Primary

MeasureTime frame
Radiographic Bone Fill in Infrabony defects at 6 months post-surgery. Timepoint: 6 months

Secondary

MeasureTime frame
1)Gain in Clinical Attachment Level(CAL) 2)Reduction in Probing Pocket Depth Timepoint: 6 months

Countries

India

Contacts

Public ContactGeeta Jagdish Bhandari

Datta Meghe Institute if Higher Education And Reaserch

gjb12286@gmail.com08237719188

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026