Evaluating the use of Rutin gel after scaling and root planing in the treatment of periodontal disease

Evaluating the clinical efficacy and GCF Superoxide Dismutase(SOD) Activity of Locally Delivered Rutin gel Adjunct to scaling and root planing in Stage II Grade A Periodontitis-A Randomised Control Trial. - nil

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084505

Enrollment

Registered

2025-04-09

Start date

Unknown

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B998- Other infectious disease

Interventions

Intervention1: SITE B: Scaling and Root Planing Followed by Locally Delivered Rutin Gel 2% at the first visit once ,topically, application is only once and observation is for 3 months Intervention2: S

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with systemic diseases. 2.Medically compromised patients, Pregnant women. 3.Endo-Perio lesion / Mucogingival Problems. 4.Subgingival restoration / Crowns / Prosthesis. 5.History of use of Antibiotics or Analgesic past 3 months. 6.Patients requiring regenerative / resective procedures. 7.Patients on active Orthodontic therapy. 8.Patients on medications / nutritional supplements.

Exclusion criteria

Exclusion criteria: 1.Patients with systemic diseases. 2.Medically compromised patients, Pregnant women. 3.Endo-Perio lesion / Mucogingival Problems. 4.Subgingival restoration / Crowns / Prosthesis. 5.History of use of Antibiotics or Analgesic past 3 months. 7.Patients on active Orthodontic therapy. 8.Patients on medications / nutritional supplements. 6.Patients requiring regenerative / resective procedures.

Design outcomes

Primary

Measure	Time frame
1.Plaque index (PI) by Sillness and Loe, 2.Gingival index (GI)by Loe and Sillness, 3.Gingival bleeding Index by Ainamo & Bay, 4.Pocket probing depth (PPD) recorded with an UNC 15 probe, 5.Relative attachment level (RAL) recorded using a stent. Timepoint: all primary outcome at baseline and after 4 weeks and 3 months.	—

Secondary

Measure	Time frame
Gingival Crevicular Fluid superoxide dismutase activityTimepoint: at baseline and after 4 weeks	—

Countries

India

Contacts

Public ContactDr Shrinidhi MS

Sharavathi Dental College and Hospital

shrinidhims75@gmail.com9945681565

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026