Study to Test the Effect of Lakshadi Guggulu with Physiotherapy in People with Knee Joint Pain (Osteoarthritis)

Randomized Double Blind Placebo Controlled Study of Lakshadi Guggulu along with Physiotherapy in Sandhigatavata with special reference to Knee Osteoarthritis - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084501

Enrollment

Registered

2025-04-09

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients showing symptoms of sandhi Gata Vata of Janu Sandhi 2. Patient having baseline knee joint pain more than 40 mm on Visual Analogue Scale (VAS) either at rest or on weight bearing activities (e.g. walking, standing, climbing staircase) during the preceding 24 hours 3. Morning stiffness less than 30 min. 4. Patients willing to follow up. 5. Patients willing to give written informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with known case of gout, rheumatoid arthritis, psoriatic arthritis, septic arthritis, and congenital joint anomalies. 2.Patients with history of rickets, osteomalacia. 3.Participants with history of auto-immune disease, uncontrolled hypertension, chronic severe respiratory disease History of life threatening cardiovascular and /or neurological event in the past one year 4.Morning stiffness more than 30 min.

Design outcomes

Primary

Measure	Time frame
To study the effect of Lakshadi Guggulu with Physiotherapy in comparison with Placebo with Physiotherapy on the basis of subjective parameters like Joint pain, swelling, stiffness, difficulty in movements using VAS (Visual Analog Scale)Timepoint: 0,15,30,45,60th day	—

Secondary

Measure	Time frame
To study the effect of Lakshadi Guggulu with physiotherapy versus placebo with physiotherapy on the basis of requirement of rescue medicines in term of dose, frequency and duration in either group from baseline till end of the study. Timepoint: 0,15,30,45,60th day;To study the effect of Lakshadi Guggulu with physiotherapy versus placebo with physiotherapy on the basis of WOMAC total score and subscore.Timepoint: 0,15,30,45,60th Day	—

Measure

Time frame

To study the effect of Lakshadi Guggulu with physiotherapy versus placebo with physiotherapy on the basis of requirement of rescue medicines in term of dose, frequency and duration in either group from baseline till end of the study. Timepoint: 0,15,30,45,60th day;To study the effect of Lakshadi Guggulu with physiotherapy versus placebo with physiotherapy on the basis of WOMAC total score and subscore.Timepoint: 0,15,30,45,60th Day

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Countries

India

Contacts

Public ContactDr Mansi Deore

Parul Institute of Ayurved and Research

dr.vaishalid@gmail.com9096082950

Outcome results