Health Condition 1: G988- Other disorders of nervous system
Conditions
Interventions
None listed
Sponsors
Dr.Abdul Majith Seeni Mohammed
Eligibility
Inclusion criteria
Inclusion criteria: 1)Patients aged 18 years and above. 2)Presenting with acute or subacute neurological symptoms suggestive of stroke (e.g., weakness, slurred speech, visual disturbances, altered sensorium). 3)Undergoing non-contrast CT (NCCT) of the brain as part of initial evaluation. 4)Undergoing MRI with diffusion-weighted imaging (DWI) within 72 hours of the NCCT for diagnostic correlation. 5)Symptom onset within 1 to 72 hours prior to imaging. 6)Informed consent obtained from the patient or legally authorized representative
Exclusion criteria
Exclusion criteria: 1)Poor-quality NCCT images due to motion artifacts or technical issues. 2)Presence of non-ischemic pathology on CT such as hemorrhage, tumors, trauma, or postoperative changes. 3)History of prior stroke in the same vascular territory. 4)Inability to undergo MRI, including contraindications such as pacemakers, metallic implants, severe claustrophobia, or clinical instability. 5)Patients who have received reperfusion therapy (e.g., thrombolysis or thrombectomy) before the baseline NCCT. 6)Incomplete clinical, laboratory, or follow-up imaging data that prevents accurate analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy of AI in detecting bilateral MCA infarcts on non-contrast CT, measured by sensitivity, specificity, PPV, NPV, and AUC-ROC.Timepoint: Real-time analysis immediately after CT scan | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Diagnostic accuracy of AI in detecting infarcts across ASPECTS severity categories (0 4, 5 7, 8 10), measured by sensitivity. 2)Time-to-diagnosis comparison between AI & radiologists, measured in minutes from CT scan completion to diagnosis report generation. 3)Clinical impact of AI on decision-making, measured by the proportion of cases with expedited thrombolysis, avoided MRI, & discordant reads requiring MRI confirmation.Timepoint: 1)Within 1 hour of AI analysis. 2)mmediately after CT scan completion. 3)Within 24 48 hours post-imaging. | — |
Countries
India
Contacts
Public ContactDrMuthiah Pitchandi
Saveetha medical college and hospital, Saveetha institute of medical and technical sciences
Outcome results
None listed