Nano-silver reinforced pit and fissure sealant and fluoride releasing pit and fissure sealant on permanent mandibular molars.

Clinical evaluation of nano-silver reinforced pit and fissure sealant and fluoride releasing pit and fissure sealant on permanent mandibular first molars : A Randomised Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2025/04/084476

Enrollment

200

Registered

2025-04-09

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K025- Dental caries on pit and fissure surface

Interventions

Intervention1: Nano-silver reinforced pit and fissure sealant: Evaluation of nano-silver reinforced pit and fissure sealant will be done at 3- and 6-month interval following placement. Control Interve

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children visiting dental clinic for the first time between 7 to 10 years of age 2. Having fully erupted mandibular first molars with deep pits and fissures.

Exclusion criteria

Exclusion criteria: 1. Children and/or Parents who are unwilling to participate in the study. 2. Children allergic to aromatic and aliphatic dimethacrylates. 3. Children showing Frankl Behavior rating 1 and II (i.e. Definitely negative and Negative). 4. Children with special health care needs.

Design outcomes

Primary

Measure	Time frame
Anatomic form, marginal adaptation, surface texture, marginal discoloration, retention, secondary caries.Timepoint: 3 months and 6 months	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactNiraj Gokhale

KAHERs KLE VK Institute of Dental Sciences, Belagavi

neerajpedo@gmail.com9535551937

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026