A study among severely injured patients undergoing emergency abdominal surgery to determine whether direct peritoneal resuscitation can lead to better abdominal wound management and prevent complications.

The success rate of Direct Peritoneal Resuscitation to achieve definitive abdominal closure in patients undergoing damage control laparotomy - a pilot randomised controlled trial - nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084463

Enrollment

Registered

2025-04-09

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Direct Peritoneal Resuscitation: Infusion of peritoneal dialysis fluid (25 g/L D-glucose, 0.567 g/L sodium chloride, 0.392 g/L sodium lactate, 0.0257 g/L calcium chloride, 0.0152 g/L ma

Eligibility

Inclusion criteria

Inclusion criteria: All patients aged 18-65 years who present as transient or non responder following trauma and undergo damage control laparotomy and deemed unfit for primary sheath closure by operating surgeon.

Exclusion criteria

Exclusion criteria: 1.Patients with severe injuries who are not expected to survive beyond 24 to 48 hrs. 2. Pregnant females 3. Patients who had undergone previous laparotomies

Design outcomes

Primary

Measure	Time frame
Achievement of abdominal fascial closureTimepoint: 7days/till discharge or demise	—

Secondary

Measure	Time frame
Time taken for definitive abdominal wound closureTimepoint: 7days/till discharge or demise;Incidence of abdominal complications(fistula formation, surgical site infection, anastomotic leak, abdominal compartment syndrome)Timepoint: Till discharge or demise;morbidity, mortality and hospital stay parametersTimepoint: Till discharge or demise	—

Countries

India

Contacts

Public ContactDr Dinesh Bagaria

Jai Prakash Narayan Apex Trauma, New Delhi

dr_bagaria@yahoo.co.in9914201918

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026