Use of Aligners for malocclusion correction and to know if there is inflammatory biomarkers and Bis-phenol A and its effects on human health.

A comparative evaluation of gingival crevicular fluid & salivary biomarkers & bisphenol A level with outsourced, inhouse and direct printed aligner for orthodontic tooth movement an invivo study - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084458

Enrollment

Registered

2025-04-09

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Aligner Therapy: Aligners are given for mild malocclusion correction and saliva and gingival crevicular fluids are collected to know about the levels of inflammatory biomarkers and bisp

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients who are healthy without any medical conditions and congenital anomaly 2. Patients who do not undergone previous orthodontic treatment or orthognathic surgeries

Exclusion criteria

Exclusion criteria: NO OTHER SYSTEMIC DISEASES NO PERIODONTAL DISEASES NO OTHER MEDICAL DISEASES

Design outcomes

Primary

Measure	Time frame
To find assosciation between salivary inflammatory biomarkers and Bis phenol A levels among different types of aligners used for tooth movement and its implications on health in South Kerala populations.Timepoint: 30 days	—

Secondary

Measure	Time frame
To compare the level of biomarkers & bisphenol A amounts between Outsourced & In house & Directly Printed AlignersTimepoint: 30 days	—

Countries

India

Contacts

Public ContactDr Vinod Krishnan

Sri Sankara Dental College Trivandrum

vikrishnan@yahoo.com9447310025

Outcome results