Comparing natural and artificial frozen embryo transfer in ovulating women

To compare the effect of endometrial preparation using natural cycle versus hormone replacement cycle on frozen embryo transfer outcomes in ovulatory infertile women : A randomised controlled trial - NIL

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084444

Enrollment

Registered

2025-04-09

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O090- Supervision of pregnancy with history of infertility

Interventions

Intervention1: NATURAL CYCLE FET: On day2 OR 3 of menstrual cycle after a basal transvaginal ultrasound and blood test for hormones and then monitored serially from day8 onwards till the time of ovula

Eligibility

Inclusion criteria

Inclusion criteria: Infertile women awaiting day 5 (blastocyst) frozen embryo transfer with Regular menstrual cycles (24 to 38 days) with a variation of 3 days

Exclusion criteria

Exclusion criteria: Anovulatory women Contraindications for hormones Presence of hydrosalpinx Uterine abnormalities Mullerian anomalies fibroid adenomyosis endometrial polyp intrauterine adhesions Chronic systemic diseases PCOS

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy rateTimepoint: 6 weeks	—

Secondary

Measure	Time frame
Ongoing pregnancy rate Early miscarriage rate Ectopic pregnancy rate Cycle cancellation rate Timepoint: 12 weeks	—

Countries

India

Contacts

Public ContactDR REKHA R

AIIMS New Delhi

drneetasingh@yahoo.com9818506855

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026