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How Bleeding Time Pulp Acidity and Inflammatory Markers affect the success of Full Pulpotomy in Patients with severe tooth pain

Correlation between Hemostatic time, Pulpal Blood pH, Cytokine levels and their effect on treatment outcome of Full Pulpotomy in Patients with Symptomatic Irreversible Pulpitis: An In VIVO study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/04/084401
Enrollment
64
Registered
2025-04-08
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Dr Siddhi Shukla
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age range of 18-45years Permanent mature first/second (upper/lower) molar tooth History of spontaneous pain lasting for a few seconds to several hours, exacerbation of pain by hot and cold fluids, radiating pain Size of exposure greater than 5mm Tooth with pulpal bleeding after full pulpotomy controlled within 10mins Positive response to cold with no sign of pulpal necrosis including swelling or sinus tract Vital mature permanent teeth with extremely deep carious lesions covering at least TWO THIRD of dentine Patients accepting to provide informed consent for treatment and recalls

Exclusion criteria

Exclusion criteria: Tooth exhibiting negative response to pulp testing Presence of a sinus tract or swelling Uncontrollable pulpal hemorrhage after the procedure lasting more than 10mins Radiograph showing abnormality around the apex of tooth, PAI greater than 2 Positive tender on percussion Patients with symptomatic disease, physical and mental disabilities Patients unwilling to continue treatment/follow up

Design outcomes

Primary

MeasureTime frame
To evaluate the impact of Hemostatic time, Blood pH and Cytokine levels on the treatment outcome of full pulpotomy in Patients with Symptomatic Irreversible PulpitisTimepoint: At Baseline and 6 months

Secondary

MeasureTime frame
To assess the correlation between hemostatic time, blood pH & cytokine levels during full pulpotomy in patients with symptomatic irreversible pulpitis in mature carious tooth.Timepoint: At Baseline & 6 months

Countries

India

Contacts

Public ContactDr Sonali Taneja

ITS-CDSR Muradnagar

sonalitaneja@its.edu.in9891688100

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026