Impact of oral zinc on serum bilirubin levels in term neonates with hyperbilirubinemia receiving phototherapy

Effect of Oral Zinc on Serum Bilirubin Levels in Term Neonates With Hyperbilirubinemia Undergoing Phototherapy : A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2025/04/084381

Enrollment

100

Registered

2025-04-08

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P598- Neonatal jaundice from other specified causes

Interventions

Intervention1: ORAL ZINC GROUP: In addition to phototherapy, the Zinc group will receive 5 mg elemental zinc i.e., 0.25 mL (Drop containing 20 mg/mL zinc sulfate) . Control Intervention1: PLACEBO GROU

Eligibility

Inclusion criteria

Inclusion criteria: Term (gestational age 37weeks and More) intramural Neonates admitted in NURSERY, UMAID HOSPITAL with Jaundice in Phototherapy Range.

Exclusion criteria

Exclusion criteria: 1 Neonates with direct hyperbilirubinemia 2 Sepsis 3 Laboratory evidence of haemolysis at enrolmemt 4 Neonates with hyperbilirubinemia in exchange transfusion range 5 On IVF 6 Major congenital anomalies 7 Respiratory disease requiring oxygen supplementation or respiratory support (CPAP, Vent)

Design outcomes

Primary

Measure	Time frame
Serum bilirubin levels in term neonates with hyperbilirubinemia undergoing phototherapy after treatment with oral zinc.Timepoint: 24 , 48 , and 72hr of zinc supplementation.	—

Secondary

Measure	Time frame
Duration of phototherapy, & hospital stayTimepoint: The time period refers to the total duration of hospital stay & total duration of phototherapy given to hyperbilirubinemia patients who are receiving oral zinc.	—

Countries

India

Contacts

Public ContactDr Sandeep Choudhary

Dr S N Medical college Jodhpur.

sandeepbugasara@gmail.com9414416405

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026