Evaluating the effect of Punarnavashtak Ghana and life style changes in Metabolic Associated Fatty Liver Disease

A randomised double-blind placebo controlled study to evaluate the effect of Punarnavashtak Ghana along with Lifestyle modification in Metabolic associated Fatty liver disease (MAFLD) with special reference to Yakrit Vikar - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084339

Enrollment

Registered

2025-04-07

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K760- Fatty (change of) liver, not elsewhere classified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient of either sex between the age of 18 to 65 year. 2.Patients fulfilling diagnostic criteria as mentioned in brief summary. 3.Sonologically diagnosed and fresh cases with grade 1 and grade 2 fatty liver . 4.Patient who are willing for participation in the trial, ready to undergo study related procedures and fill the consent form.

Exclusion criteria

Exclusion criteria: 1.Alcoholic steatohepatitis 2.K/C/O hepatitis B and C, cirrhosis of liver, Jaundice 3.Pregnant and lactating women. 4.The prescription of medication which would cause MAFLD ex.tamoxifen 5.Already taking supplementary medicine for NAFLD 6.Patient who has past history of cardiac Arrythmia, Acute coronary syndrome, myocardial infarction, symptomatic patient with clinical evidence of cardiac failure.

Design outcomes

Primary

Measure	Time frame
To study effect of Punarnavashtak Ghana with life style modification in comparision with placebo with life style modification on the basis of subjective parameter from baseline to end of study.Timepoint: 0 DAYS 30 DAYS 60 DAYS 90 DAYS	—

Secondary

Measure	Time frame
To study the the effect of Punarnavashtak Ghana with life style modification in comparision with placebo on 1.Lipid profile 2.SGOT (AST), SGPT(ALT) levels 3.Weight and BMI 4.FIB-4 score 5.APRI score 6. BARD score from baseline to end of study.Timepoint: 0 DAYS & 90 DAYS	—

Countries

India

Contacts

Public ContactDr Devkanya Khatediya

Parul Institute of Ayurved and research

dr.vaishalid@gmail.com9096082950

Outcome results