Health Condition 1: O140- Mild to moderate pre-eclampsia Health Condition 2: O141- Severe pre-eclampsia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - pregnant women with preeclampsia on magnesium sulfate regimens - BMI between 18.5 and 24 - elective C-section at term pregnancy under spinal anesthesia.
Exclusion criteria
Exclusion criteria: - regional anesthesia refusal, - regional anesthesia contraindications (e.g., Thrombocytopenia, coagulopathy), - conditions associated with an increased level of PPH risk, such as placenta previa, placental abruption, and multiple gestation, - pregnancy-related complications as gestational diabetes, or pre-existing diseases as insulin-dependent diabetes, cardiovascular or renal diseases, hypo/hyperthyroidism because these conditions might interfere with the hemodynamic parameters.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare blood pressure betwen two groups.Timepoint: Pre operative and Intra operative 1, 5, 10, 15, 30, 60 minutes after administration of study drugs. | — |
Secondary
| Measure | Time frame |
|---|---|
| - to compare other hemodynamic parameters such as HR, SpO2. - to compare need for vasopressor use. - to compare Uterine contraction, need for extra uterotonic, PPH incidence. - to study side effects of study drugs. Timepoint: Pre operative and Intra operative 1, 5, 10, 15, 30 and 60 minutes after administration of study drugs. | — |
Countries
India
Contacts
Jalpaiguri Govt Medical College and hospital