Spinal anesthesia and nerve blocks: A comparison of their effects on post-surgery recovery after below-knee surgery

Comparative study of Spinal anaesthesia and Peripheral nerve block on Post operative quality of recovery in below knee surgery - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084212

Enrollment

Registered

2025-04-07

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Spinal Anaesthesia: Spinal anaesthesia will be achieved by injecting 2.5ml or 12.5mg of Injection Bupivacaine heavy 0.5% with addition of 0.5ml or 25mcg of Injection Fentanyl under all

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients undergoing below knee surgery 2.American society of Anaesthesiologists grade 1 and 2 3. Mini Mental State Examination score more than 24 4. Duration of surgery less than 2 hours

Exclusion criteria

Exclusion criteria: 1.Patients allergic to local anaesthetic agents 2.Bleeding disorders 3.Localised infections 4.Neurological disease 5.Anatomical abnormalities of spinal column 6.Respiratory/cardiac disease 7.Body mass index more than 32kg/m2 8.Patient not giving consent 9.Patients with polytrauma, cardiothoracic, CNS injury

Design outcomes

Primary

Measure	Time frame
To study and compare Spinal Anaesthesia and Peripheral nerve blocks Popliteal Sciatic and Saphenous nerve block on Post operative quality of recovery in below knee surgeryTimepoint: Intraoperatively vitals will be recorded every 15 minutes. Postoperatively, The quality of post operative functional recovery will be assessed using the QoR40 questionnaire, which assess five dimensions of recovery which are 1. Physical comfort (12 items), 2. Emotional state (9 items), 3. Physical independence (5 items), 4. Psychological support (7 items) and 5.Pain (7 items). Each item will be rated on a 5 Point Likert scale: none of the time, some of the time, usually, most of the time and all of the time. The total score on the QoR-40 ranges from 40 (poorest quality of recovery) to 200 (best quality of recovery). The QoR-40 will be studied three times: the day before surgery, Post operative day-1 and 2 between 8-10pm.	—

Measure

Time frame

To study and compare Spinal Anaesthesia and Peripheral nerve blocks Popliteal Sciatic and Saphenous nerve block on Post operative quality of recovery in below knee surgeryTimepoint: Intraoperatively vitals will be recorded every 15 minutes. Postoperatively, The quality of post operative functional recovery will be assessed using the QoR40 questionnaire, which assess five dimensions of recovery which are 1. Physical comfort (12 items), 2. Emotional state (9 items), 3. Physical independence (5 items), 4. Psychological support (7 items) and 5.Pain (7 items). Each item will be rated on a 5 Point Likert scale: none of the time, some of the time, usually, most of the time and all of the time. The total score on the QoR-40 ranges from 40 (poorest quality of recovery) to 200 (best quality of recovery). The QoR-40 will be studied three times: the day before surgery, Post operative day-1 and 2 between 8-10pm.

—

Secondary

Measure	Time frame
To study and compare peri-operative hemodynamic parameters. Timepoint: To record Heart rate, Systolic and Diastolic Blood pressure, Oxygen saturation, Visual Analog scale for pain at 1hour, 2hour, 4hour, 6hour, 10hour, 16hour, 24hour, 36hour, 48hour, 72hour;To study and compare time of onset of Sensory and Motor blockadeTimepoint: Record time of onset of sensory and motor blockade post procedure.	—

Countries

India

Contacts

Public ContactDr Sumita Kumari

Institute of Medical Sciences, Banaras Hindu University

drsumita.1@gmail.com8765514029

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026