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Effect of pre-operative nebulisation of magnesium sulphate for reducing the incidence of post operative sore throat

Comparison of two different doses of pre-operative nebulisation of magnesium sulphate in reducing the incidence of post operative sore throat following endotracheal intubation in patients undergoing surgery under general anaesthesia - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/084149
Enrollment
90
Registered
2025-04-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis

Interventions

Intervention1: Preoperative nebulization of magnesium sulfate to decrease the incidence of post operative sore throat: Pre-operative nebulisation of magnesium sulphate 250mg in reducing the incidence

Sponsors

Dr. Khullar Kamnong
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age between 20 to 65 years, American society of anaesthesiologists grading 1 and 2, Mallampati scoring 1 and 2, duration of surgery more than 1 hour

Exclusion criteria

Exclusion criteria: Patient refusal, allergy to drugs, head and neck surgery, American society of anaesthesiologists grade 3 and 4, patients with upper respiratory tract infection, neuromuscular diseases, patients with nasal and throat pack, age less than 20yrs and more than 65years

Design outcomes

Primary

MeasureTime frame
1. Post operative sore throat at rest 2. Post operative sore throat on swallowingTimepoint: 0hours, 2 hours, 4hours, 6hours, 10hours, 24hours

Secondary

MeasureTime frame
Laryngeal complaints such as cough, hoarseness of voice, nausea and vomiting, respiratory depression and hypotensionTimepoint: 0hours, 2 hours, 4hours, 6hours, 10hours, 24hours

Countries

India

Contacts

Public ContactDr Kiwi Mantan

Sardar Patel Medical College

kiwivyas@gmail.com9929092702

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026