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Comparison of blood pressure and heart rate changes using two muscle relaxant drugs for intubation of patients undergoing Laparoscopic appendicectomy.

Comparison of haemodynamic changes with Rocuronium vs. Vecuronium for intubation of patients undergoing Laparoscopic appendicectomy under general anaesthesia: a double blind randomized controlled trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/084125
Enrollment
96
Registered
2025-04-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K389- Disease of appendix, unspecified Health Condition 2: K358- Other and unspecified acute appendicitis Health Condition 3: K36- Other appendicitis Health Condition 4: K388- Other specified diseases of appendix Health Condition 5: K37- Unspecified appendicitis

Interventions

Intervention1: General anaesthesia with Rocuronium: To determine haemodynamic changes with the drug for the 1st 30 minutes after intubation and note any adverse events for 12 hours after completion of

Sponsors

Department of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.American Society of Anaesthesiologists (ASA) grade I and II 2.Patients undergoing Laparoscopic appendicectomy under General anaesthesia

Exclusion criteria

Exclusion criteria: 1.Pregnant 2.Lactating mothers 3.Patient with hypersensitivity to any of the research drugs 4.Patients undergone clinical trial within 3 months 5.Anticipated difficult airway 6. Patients having contraindication for laparoscopic surgeries 7.Severe Systemic diseases(Hypertension, Diabetes Mellitus, Seizure Disorder, Neurological Disorders, etc.)

Design outcomes

Primary

MeasureTime frame
To compare changes in the mean artrial blood pressure and heart rate using Rocuronium and Vecuronium in patients undergoing laparoscopic appendicectomy under general anaesthesiaTimepoint: 1.Before intubation 2.Just after intubation 3.15 minutes after intubation 4.30 minutes after intubation

Secondary

MeasureTime frame
To compare the ease of intubation between the two groupsTimepoint: During intubation;To compare the adverse events of the two muscle relaxants usedTimepoint: 12 hours post-operative period

Countries

India

Contacts

Public ContactPriya Gupta

College of Medicine and Sagore Dutta Hospital

priya140899@gmail.com9123872867

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026