A clinical trial comparing wound healing and wound complications between standard of care dressing and negative pressure wound therapy in post-operative limb salvage surgery of bone tumours around the knee.

Comparison between Negative Pressure Wound Therapy and Standard-of-Care in Post-operative wound healing and wound complications after limb salvage surgery in bone tumours. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084093

Enrollment

Registered

2025-04-04

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C402- Malignant neoplasm of long bones of lower limb

Interventions

Intervention1: Negative pressure wound therapy: Negative pressure wound therapy is a medical device which uses negative pressure to provide suction over wounds, closed or open, aiding in reducing woun

Eligibility

Inclusion criteria

Inclusion criteria: 1. Bone tumours around the knee. 2. Should be willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Any contraindications to negative pressure wound therapy. 2. Bone tumours with active infection over surgical site. 3. Bone tumours requiring revision surgery. 4. Allergy to adhesive dressing. 5. Bone tumours requiring amputation as primary. 6. Any on-going bleeding disorder or coagulopathy. 7. Co-morbidities: Diabetes mellitus, peripheral vascular disease. 8. Patient receiving local radiation. 9. Patient with deranged albumin levels. 10. Refuses participation.

Design outcomes

Primary

Measure	Time frame
Wound healing by measuring the time taken by the wound to dry as per Southampton Wound Grading of Grade 2 or lessTimepoint: 30 days post-operative	—

Secondary

Measure	Time frame
Wound complications like: 1. Wound dehiscence 2. Surgery to operative site within 30 dats post-operatively . 3. Increased surgical drain volume. 4. Surgical site infectionsTimepoint: 30 days post-operative	—

Countries

India

Contacts

Public ContactShanborlang Siangshai

Postgraduate Institute of Medical Education and Research, Chandigarh

vikasbachhal@gmail.com7087928664

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026