Health Condition 1: C00-D49- Neoplasms
Conditions
Interventions
None listed
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: Women aged 18 years above Women who Underwent cervical cancer screening by VIA, cytology and HPV DNA test Women Underwent diagnostic evaluation by Colposcopy
Exclusion criteria
Exclusion criteria: Inadequate data despite the attempt will be excluded from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Prevalence and Determinants Of HPV infection & CIN: a. proportion of screened women testing positive for HPV infection. b. Prevalence of different grades of cervical Intraepithelial Neoplasia (CIN1, CIN2, CIN3) c. Association of Socio-demographic, clinical, and behavioral factors with HPV infection and CIN. 2. HPV Genotype Distribution and Association with Cervical Lesions: a. Frequency of different HPV genotypes detected. b. association of specific high-risk HPV genotypes with histologically confirmed precancerous (CIN2/3) and cancerous lesions. 3. Association Between HPV infection and cytological abnormalities: a. Proportion of HPV-positive women with abnormal cytology results. b. association between HPV genotype and cytological abnormalities such as ASCUS,LSIL and HSIL Timepoint: 12 Months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Comparison of Cervical Cancer Screening Methods & Diagnostic Accuracy: a)Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of different screening methods (VIA, HPV testing, Pap smear, Colposcopy). b)Agreement between different screening modalities and histopathological findings. 2.Performance of Colposcopy in VIA & HPV-Based Screening Services: a) Diagnostic accuracy of Colposcopy in detecting cervical precancerous/cancerous lesions. b) Agreement between Colposcopic findings and histopathological findings. Timepoint: 12 Months | — |
Countries
India
Contacts
Public ContactDr Sharmila Pimple
Tata Memorial Hospital
Outcome results
None listed