Health Condition 1: - Health Condition 2: C00-D49- Neoplasms
Conditions
Interventions
Intervention1: MEGESTROL: To compare the safety and efficacy weight gain and appetite improvement of megestrol when given in two doses160mg per day
Control Intervention1: MEGESTROL: To compare the saf
Sponsors
Tata Memorial centre Administrative Research Council
Eligibility
Inclusion criteria
Inclusion criteria: 1 Patients with 18 years and above 2 Advance Stage Patients with confirmed diagnosis of ACS 3 Loss of Greater than 5 Percent pre illness of body weight in the previous 3 months 4 Life expectancy of Greater or Equal to 4 months 5 Patients receiving palliative treatment or supportive care
Exclusion criteria
Exclusion criteria: 1 Patient with history of hypertension and diabetes mellitus 2 Mechanical obstruction to feeding 3 Pregnant women or breast-feeding women 4 History of thromboembolism and edema 5 Patients already on alternative medications that may significantly show improvement in weight gain 6 Patients refuse to consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome 1. To compare weight and appetite improvement in participants in both arms. Secondary Outcome ââ?¬â?? 1. To compare quality of life at baseline and 4 weekly till the primary endpoint. 2. To compare adverse events in both arms.Timepoint: 12weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Outcome ââ?¬â?? 1. To compare quality of life at baseline and 4 weekly till the primary endpoint. 2. To compare adverse events in both arms.Timepoint: 12weeks | — |
Countries
India
Contacts
Public ContactDr Kunal Ranjan Vinayak
HBCH AND MPMMCC Varanasi
Outcome results
None listed