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EFFECTS OF DIFFERENT ADJUVANTS ON HEMODYNAMIC PARAMETERS IN PATIENTS UNDERGOING SPINAL ANESTHESIA.

COMPARISON OF HEMODYNAMIC PROFILES OF DIFFERENT ADJUVANTS USED IN PATIENTS UNDERGOING SPINAL ANAESTHESIA: A PROSPECTIVE OBSERVATIONAL STUDY - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/083995
Enrollment
126
Registered
2025-04-03
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Buprenorphine: Spinal anaesthesia is administered using 0.5% Bupivacaine heavy (3 ml) with 60 mcg of Buprenorphine as an adjuvant to observe the hemodynamic parameters and analgesic eff

Sponsors

SRM Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA physical Status classification 1 and 2 2.Patient admitted for General surgeries /obstetrics surgeries/orthopedic surgeries are included 3.Hemodynamicaly stable patient 4.Surgeries of lower limbs

Exclusion criteria

Exclusion criteria: 1.ASA physical status classification 3 and 4. 2.Patient refusal /failed Spinal anesthesia 3.History of coagulopathy 4.Infection at the site of injection 5.Severe spinal deformity 6.Allergy to drugs 7.Patient with preexisting neurological deficits

Design outcomes

Primary

MeasureTime frame
To compare and observe the hemodynamic profiles between fentanyl and buprenorphine. Timepoint: Assessment will include pre-spinal, after spinal administration, 5, 10, and 15 minutes followed by every 15 minutes until the end of the surgery.

Secondary

MeasureTime frame
To assess the analgesic effects, postoperative hemodynamic parameters and complications.Timepoint: Every hour in the postoperative period until the 4th hour

Countries

India

Contacts

Public ContactDr C Gokulakrishnan

SRM medical college and hospital SRM Nagar Potheri

gokulakc@srmist.edu.in8056417783

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026