Health Condition 1: F112- Opioid dependence
Conditions
Interventions
Intervention1: Add-on Flupirtine: Tramadol 300-400mg (3 divided doses) + Clonidine 0.2-0.4mg (2-3 divided doses) + Lorazepam 1-2mg HS + Flupirtine 100mg TDS
Note- Tramadol will be tapered and stoppe
Sponsors
Bhavneesh Saini
Eligibility
Inclusion criteria
Inclusion criteria: 1. Subjects who give written informed consent for the study. 2. Subjects aged between 18 to 60 years of age. 3. Subjects diagnosed with opioid (heroin) dependence (F11.2) as per ICD-10 and admitted in psychiatry ward of dept. of Psychiatry, GGSMCH, Faridkot for opioid detoxification. 4. Subjects having at least mild pain as part of opioid withdrawal, i.e., scoring at least 3mm on VAS (Visual Analog Scale) and at least 1 point on COWS (Clinical Opiate Withdrawal Scale) scale Bone or joint aches item.
Exclusion criteria
Exclusion criteria: 1. Subjects with history of psychiatric illness and/or intellectual disability. 2. Subjects with neurological illness like Dementia, Parkinson disease, SOL (space occupying lesion), Stroke, etc. 3. Patient with Head Injury. 4. Subjects with any severe medical or surgical illness or taking concomitant medication for such illnesses, e.g., anticoagulants. 5. Subjects dependent upon substance(s) other than heroin, except nicotine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain Score on Visual Analog Scale (VAS) and Clinical Opiate Withdrawal Scale (COWS) score.Timepoint: Everyday till discharge (7-10 days of stay) | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactBhavneesh Saini
Guru Gobind Singh Medical College and Hospital, Faridkot
Outcome results
None listed