Health Condition 1: I348- Other nonrheumatic mitral valve disorders
Conditions
Interventions
None listed
Sponsors
Rajendra Institute of Medical Sciences Ranchi
Eligibility
Inclusion criteria
Inclusion criteria: ASA Grade 1, 2 and 3; 18-59 years; posted for elective cardiovascular surgery which includes: mitral valve replacement, double valve replacement, CABG and correction of septal wall defects.
Exclusion criteria
Exclusion criteria: ASA grade 4 and above , patients with severe infection, cardiac/liver/kidney disease, congenital disorder, obesity or underweight patients, cancer patients, patients who are already taking opioids in any form, pregnant patients and patients with neurological illnesses.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Opioid requirement in postoperative period in patients with genetic polymorphism with OPRM 1 A118G.Timepoint: From the end of surgery (baseline) till 36 hours in postoperative period. | — |
Secondary
| Measure | Time frame |
|---|---|
| A. To assess post-operative pain at 8, 24 & 36 hours after cardiovascular surgery using NRS rating scale. B. To analyse the incidence of postoperative nausea & vomiting at 8, 24 & 36 hours after cardiovascular surgery using the NRS rating scale. C. To analyse sedation score at 8, 24 & 36 hours after cardiovascular surgery using RASS scoring system.Timepoint: A. From end of surgery ( baseline) till 36 hours in post operative period. B. From end of surgery ( baseline) till 36 hours in post operative period. C. From end of surgery ( baseline) till 36 hours in post operative period. | — |
Countries
India
Contacts
Public ContactDr Praveen Kumar Tiwary
Rajendra Institute of Medical Sciences, Ranchi
Outcome results
None listed