To assess the efficiency of different methods for disinfecting of deciduous teeth against Escherichia coli in root canal that is infected.

Comparison of Antibacterial Efficacy of Different Techniques for Disinfection of Primary Teeth Against Common Pathogen (Enterococcus faecalis) in Infected Root Canal: An Ex Vivo Study - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/083884

Enrollment

Registered

2025-04-02

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: 2% Chlorhexidine: 2% Chlorhexidine at higher concentrations for 30 seconds works as an antimicrobial agent by cytoplasmic precipitation and eventually causing cell lysis when used for d

Eligibility

Inclusion criteria

Inclusion criteria: Children having long standing history of dull pain. Clinically nonvital tooth. Deciduous teeth having necrotic pulp. Deciduous teeth having sinus tract opening. Deciduous teeth having at least two thirds of root length.

Exclusion criteria

Exclusion criteria: Deciduous teeth having more than 1/2 of the root length resorbed. Deciduous teeth with Obliterated canal. Medically compromised child. Children who have taken antibiotics within past 2 months.

Design outcomes

Primary

Measure	Time frame
To determine the suitable methods for root canal disinfection. Irrigating agents decrease bacterial counts in canals of deciduous teeth roots to achieve a successful treatment outcome. Therefore, this study aims at helping clinicians in selecting a suitable irrigation method such as Chlorhexidine (CHX), sodium hypochlorite (NaOCl), Diode Laser, Ozonated water and Apple cider vinegar out of all diode laser will be most effective in decreasing the bacterial counts in deciduous teeth.Timepoint: 1 week	—

Measure

Time frame

To determine the suitable methods for root canal disinfection. Irrigating agents decrease bacterial counts in canals of deciduous teeth roots to achieve a successful treatment outcome. Therefore, this study aims at helping clinicians in selecting a suitable irrigation method such as Chlorhexidine (CHX), sodium hypochlorite (NaOCl), Diode Laser, Ozonated water and Apple cider vinegar out of all diode laser will be most effective in decreasing the bacterial counts in deciduous teeth.Timepoint: 1 week

—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Antra

Sardar Patel Post Graduate institute of dental and medical sciences

dranshulsharma84@gmail.com9415301634

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026