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The effect of varied concentration of Fluoride mouth wash on the cells of oral cavity during braces treatment

Comparative impact of Fluoride mouthwash concentrations on Cytotoxicity, Genotoxicity and DNA repair in Oral Mucosa during orthodontic treatment- A Randomized Control Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/083858
Enrollment
57
Registered
2025-04-02
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M264- Malocclusion, unspecified

Interventions

Intervention1: Fluoride Mouthwash: 220 ppm mouthwash twice a day for One year, 480 ppm mouthwash twice a day for One year Control Intervention1: Chlorhexidine Mouthwash: 0.2% mouthwash twice a day for

Sponsors

Dr Arulantony W
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing fixed orthodontic treatment with NiTi arch wires, aged 13-35 years, good general health.

Exclusion criteria

Exclusion criteria: Patients with systemic diseases affecting oral health, history of allergy to nickel or fluoride, current use of medications affecting oral mucosa.

Design outcomes

Primary

MeasureTime frame
Cytotoxic effects , Genotoxic effectsTimepoint: Before start of treatment, 6 months—

Secondary

MeasureTime frame
DNA repairTimepoint: 12 months—

Countries

India

Contacts

Public ContactDr Arulantony W

Chettinad Dental College and Research Institute

saro_sk@yahoo.com9092498082

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026