Study of skull base Osteomyelitis- Role of CT Scan and MRI in diagnosing disease.

STUDY OF SKULL BASE OSTEOMYELITIS- Role of CT an MRI in staging of the disease and comparison of CT scan and MRI findings. Role of Early intervention in prognosis - SBO MRI

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/083795

Enrollment

Registered

2025-04-01

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H602- Malignant otitis externa Health Condition 2: M952- Other acquired deformity of head Health Condition 3: B950- Streptococcus, group A, as the cause of diseases classified elsewhere

Interventions

Intervention1: Computerised Tomography Scanning of Temporal Bone and Skull and MRI are performed at presentation and iv antibiotics at presentation vs delayed beyond 5 days. Diabetic patients are star

Eligibility

Inclusion criteria

Inclusion criteria: Presence or absence of 4 criteria: 1. Presence or absence Diabetes Mellitus 2. Age more than 70 years. 3. Involvement of bone and soft tissue. 4. MRI findings and Ct scan findings. 5. Presence of Cranial N palsy 6. Progression free survival 7. Glycemic control and role of insulin

Exclusion criteria

Exclusion criteria: 1. HIV related Skull base osteomyelitis 2. Trauma and cancer related osteomyelitis

Design outcomes

Primary

Measure	Time frame
Use of MRI to identify the early disease and its role in determining the extent of the disease and its complications is used in grading the disease severity . Its use to help initiate early intervention with IV antibiotics and Insulin is compared to those patients who failed to present themselves early to the hospital and hence a delay in management.Timepoint: 2 weeks after Use of MRI in determining the extent of the disease and its complications is used in grading the disease severity . Its use to help initiate early intervention with IV antibiotics and Insulin is compared to those patients who failed to present themselves early to the hospital and hence a delay in management.	—

Measure

Time frame

Use of MRI to identify the early disease and its role in determining the extent of the disease and its complications is used in grading the disease severity . Its use to help initiate early intervention with IV antibiotics and Insulin is compared to those patients who failed to present themselves early to the hospital and hence a delay in management.Timepoint: 2 weeks after Use of MRI in determining the extent of the disease and its complications is used in grading the disease severity . Its use to help initiate early intervention with IV antibiotics and Insulin is compared to those patients who failed to present themselves early to the hospital and hence a delay in management.

—

Secondary

Measure	Time frame
unresolved infection and deathTimepoint: 2 months	—

Countries

India

Contacts

Public ContactDr Choudhary satyanarayana chalasani

Annamalai university

cvschoudhary@yahoo.co.in9502191823

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026