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to compare the improvement in post operative complications and outcomes and the neutrophil/lymphocyte markers between preoperative carbohydrate loading and conventional fasting groups in elective colorectal cancer surgeries

Effects of preoperative oral carbohydrate loading on postoperative outcomes and change in neutrophil/lymphocyte ratio and following elective colorectal cancer surgery : A randomized controlled study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/083793
Enrollment
68
Registered
2025-04-01
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C18- Malignant neoplasm of colon Health Condition 2: C19- Malignant neoplasm of rectosigmoidjunction Health Condition 3: C20- Malignant neoplasm of rectum

Interventions

Intervention1: maltodextrin solution 12.5g/100ml: The patient in OCL group (oral carbohydrate loading) will receive 400 ml of clear carbohydrate drink (maltose dextrin,12.5g of carbohydrate per 100ml)

Sponsors

Jinendra Jain
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients admitted for elective colorectal surgery in JIPMER more than 18 years of age

Exclusion criteria

Exclusion criteria: 1. Recurrent CRC 2. Emergency surgeries 3. Metastatic disease 4. Known cases of chronic diseases such as uncontrolled diabetes mellitus, uncontrolled hypertension, hematological illnesses. 5. Cases of psychiatric illnesses, in which cases consent will not be there.

Design outcomes

Primary

MeasureTime frame
To compare the effect of oral carbohydrate loading and preoperative prolonged fasting on The post operative complications on the basis of Clavein-Dindo classification, and GRADE 1Elevated serum creatine Confusion GRADE 2Pneumonia Delirium Uro-infection Wound infection GRADE 3Anastomotic leakage Ileus Abdominal wall dehiscence Reoperation GRADE 4Respiratory failure Renal failure Septic Shock MODS GRADE 5Death of patient Timepoint: upto 30 days post operatively—

Secondary

MeasureTime frame
2. The post operative time to discharge based on fulfillment of the following criteria: A. Passage of stools/ Functional moving stoma B. Tolerating soft diet C. No or minimal tolerable abdominal pain D. Drain removed/ Drain output less than 30ml E. No SSI requiring in hospital dressing and IV antibiotics Timepoint: upto point of discharge;to compare the effect of oral carbohydrate loading group and prolonged fasting group over post operative neutrophil to lymphocyte ratio and the significance of changeTimepoint: preoperative day before surgery post operative day 1,3 and 5—

Countries

India

Contacts

Public ContactSreenath G S

Jawaharlal Institute of Postgraduate Medical Education and Research

dr.sreenathgs@gmail.com9486690883

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026