Enamel Remineralization in Clear Aligner Patients Using a Novel Remineralizing Solution: A Clinical Study

Evaluation of Enamel Remineralization Using a Novel Remineralizing Solution in patients undergoing Clear Aligner Therapy - A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/083789

Enrollment

Registered

2025-04-01

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified

Interventions

Intervention1: Aligner trays with Novel Remineralizing Solution: Patients undergoing aligner treatment will be asked to use a novel remineralizing solution on the active surface of their trays followi

Eligibility

Inclusion criteria

Inclusion criteria: The patients age range between the age from 14 to 40 years old Gender can be males or females Good oral hygiene with a plaque index score 0 or 1 good general health patient compliance Active noncavitated carious white spot lesions Undergoing clear aligner therapy treatment No systemic diseases or concomitant medication affects salivary fow in order not to negatively affect the remineralizing process

Exclusion criteria

Exclusion criteria: Patients undergoing conventional orthodontic treatment Age outside 14 to 40 years Systemic diseases or medication Smoking or tobacco use Pregnancy and lacation

Design outcomes

Primary

Measure	Time frame
Enamel remineralization potentialTimepoint: 3 months	—

Secondary

Measure	Time frame
Colour stabilityTimepoint: 15 days of aligner use	—

Countries

India

Contacts

Public ContactNavaneethan R

SAVEETHA DENTAL COLLEGE

navaneethan@saveetha.com9962787531

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026