Moringa oleifera leaf extract oral gel vs retino-a cream in treatment of homogenous oral leukoplakia.

Evaluating the therapeutic efficacy of Moringa oleifera leaf extract oral gel versus Retino-A cream in oral homogenous leukoplakia. A double blinded randomized controlled trial. - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/083778

Enrollment

Registered

2025-04-01

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K132- Leukoplakia and other disturbancesof oral epithelium, including tongue

Interventions

Intervention1: Moringa oleifera leaf extract oral gel: Evaluating therapeutic efficacy of Moringa oleifera leaf extract oral gel for Homogenous Oral Leukoplakia and will be reviewed periodically at an

Eligibility

Inclusion criteria

Inclusion criteria: 1.Subjects willing to participate in the study. 2.Subjects diagnosed with homogenous leukoplakia clinically.

Exclusion criteria

Exclusion criteria: Non homogenous Leukoplakia. Pregnant and lactating women.

Design outcomes

Primary

Measure	Time frame
Reduction in size of Homogenous Oral Leukoplakia lesionTimepoint: Baseline, 2nd week, 4th week, 6th week and 8th week	—

Secondary

Measure	Time frame
No secondary outcome measured. Any adverse events will be notedTimepoint: Baseline, 2nd week, 4th week, 6th week and 8th week	—

Countries

India

Contacts

Public ContactDr.N.Purna chandra rao naik

Sibar institute of dental sciences

drpurnaoralmed@sids.ac.in9989857600

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026