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In this study, we will compare the effect of two doses of dexmedetomidine, an analgesic and sedative on recovery of gastrointestinal function in postoperative period.

Comparison of effect of two different doses of intraoperative Dexmedetomidine infusion on recovery of gastrointestinal movement in adult patients undergoing emergency abdominal surgery : A randomised clinical trial - NIL

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/083757
Enrollment
120
Registered
2025-03-28
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K95- Diseases of the digestive system

Interventions

Intervention1: General Anaesthesia: After arrival in the operating room, routine monitoring devices will be attached. All patients will be premedicated with intravenous glycopyrrolate 0.2mg followed b

Sponsors

Indira Gandhi Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Body weight 50 - 70 kg Patient undergoing emergency abdominal surgeries

Exclusion criteria

Exclusion criteria: Patient refusal Preoperative use of opioids Bradycardia Heart block greater than first degree Preoperative use of antihypertensive drugs containing clonidine or an a2-agonist Difficulty in communication Abnormal liver or renal function Bowel disease (Ulcerative Colitis, Crohns disease and IBS)

Design outcomes

Primary

MeasureTime frame
time to first flatus in postoperative periodsTimepoint: any time during the postoperative period corrected to the nearest hour

Secondary

MeasureTime frame
postoperative gastrointestinal function measured by I-FEED scoring systemTimepoint: measure over first 72 hr of postoperative period;time to first fecesTimepoint: any time during the postoperative period corrected to nearest hour;time to first oral feedingTimepoint: any time during the postoperative period corrected to nearest hour;incidence of deliriumTimepoint: measure twice daily for first 3 days during the postoperative period;pain scoreTimepoint: measure for 7 postoperative days;sleep qualityTimepoint: measure for 7 postoperative days;postoperative nausea & vomitingTimepoint: measure for 7 postoperative days;hospital costsTimepoint: total amount of money that will spend during hospital stay;hospital length of stayTimepoint: total number of days patient will spend in hospital

Countries

India

Contacts

Public ContactNITIN KUMAR

INDIRA GANDHI INSTITUTE OF MEDICAL SCIENCES

kumarnitin516@gmail.com8076070302

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026