Skip to content

Effect on inflammatory markers by use of powdered oxidised regenerated cellulose (ORC) for achieving haemostatis during laparoscopic cholecystectomy

Comparison of effect of powdered oxidised regenerated cellulose (ORC) on inflammatory markers and achieving hemostasis in laparoscopic cholecystectomy- a randomised controlled study - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/03/083703
Enrollment
50
Registered
2025-03-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K801- Calculus of gallbladder with othercholecystitis

Interventions

Intervention1: Application of Powdered Oxidised regerated cellulose in the liver bed for completion of hemostatsis after achieving major hemostasis on the liver bed from arterial spurters or venous bl

Sponsors

Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Gall Stone disease presenting to Surgery OPD of Lok Nayak Hospital and planned for laparoscopic cholecystectomy.

Exclusion criteria

Exclusion criteria: 1. Empyema gall bladder 2. Needle aspiration of gall bladder for decompression 3. Intraoperative Biliary spillage 4. Subtotal cholecystectomy 5. Requirement of placement of intra abdominal drain during surgery

Design outcomes

Primary

MeasureTime frame
Change in levels of inflammatory markers (Highly sensitive C Reactive Protein ,Procalcitonin) levels postoperatively (at 24 hours) in comparison to preoperative (within 24 hours prior to surgery)valuesTimepoint: 24 hours post surgery

Secondary

MeasureTime frame
Achieve hemostasisTimepoint: During procedure;Change in levels of Total leukocyte count , differential leukocyte count, absolute neutrophil count postoperatively (at 24 hours) in comparison to preoperative (within 24 hours prior to surgery)valuesTimepoint: 24 hours post surgery

Countries

India

Contacts

Public ContactKanishh Tayal

Maulana Azad Medical College And Associated Lok Nayak Hospital

drdeepakghuliani@gmail.com9899326388

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026