Health Condition 1: G00-G99- Diseases of the nervous system
Conditions
Interventions
Intervention1: levobupivacaine group: Patients undergoing the study were randomly assigned to receive intranasal packing with 15 mL of 0.5% levobupivacaine combined with 60mg of ephedrine (2 mL) Prior
Sponsors
Mahatma Gandhi Medical College and Hospital Jaipur
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged between 18 to 65 years. 2. Both male and female patients. 3. American Society of Anesthesiologists physical class 2 or 3. 4. Scheduled for endoscopic binostril transnasal transsphenoidal (TNTS) surgery. 5. Diagnosis of sellar or suprasellar tumors.
Exclusion criteria
Exclusion criteria: 1. Refusal to provide informed consent. 2. Preoperative cerebrospinal fluid leak. 3. Known allergy to local anesthetic agents. 4. Preoperative cardiac arrhythmias. 5. History of seizure disorders. 6. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the hemodynamic changes between both groups and report adverse effects if any. Timepoint: 3 min,(Post tracheal intubation),At insertion of endoscope,3 min. later, At start of mucosal dissection,1 min/2min/3min/4min/5min,10 min,20 min,30 min,40 min,50 min,60 min,1hr 30 min,2 hr,2hr 30 min,3hr.,At tracheal extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare intraoperative bleeding in the surgical field between both groups. Timepoint: Boezaart surgical field Grade 1 ,2,3,4,5;To compare the time to extubation of patients between both groups.Timepoint: Time to be recorded from the time of stopping the inhalation agent till the removal of endotracheal tube | — |
Countries
India
Contacts
Public ContactDr. Sunita Sharma
Mahatma gandhi medical college and hospital jaipur
Outcome results
None listed